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May 20, 2024
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2023-2024 College Catalog
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BI 246 MOLECULAR AND DEVELOPMENTAL BIOLOGY
The Molecular and Developmental Biology course covers cellular, molecular, biochemical, and genetic events with a greater emphasis on mechanisms related to development: how a single cell develops into a complex and well-structured multicellular organism. This course is established to introduce students to theories and proposed tools of the developmental process in several model organisms such as C. e/egans, Drosophila, Zebrafish, and plant species. Emphasis will be given to the developmental process relevant to human development, regenerative medicine, health, and disease. Molecules regulating differentiation, morphogenesis, and growth, expression of gene regulation during the developmental process, cellular signaling, cell lineage, the role of stem cells in human development and potential for treating disease will be studied. Laboratory experiment focuses on early development of some of the model organisms employing latest and broad range of molecular and genetic methodologies related to DNA, RNA, micro RNA, non-coding RNA processing, RNA surveillance pathways, alternative splicing, DNA/RNA- protein complexes. Lab techniques include CRISPR/Cas9 system, Real time-PCR, western blot, nucleic acid fragment analysis, deep sequencing, and transcriptome analysis. Lecture: 3 hours per week. Lab: 3 hours per week. 4 Credits Prerequisites: BI 120 and CH 120
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